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Isabela Carvalhal

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Review Open access Oct 2026

Angiography-Derived Versus Wire-Based Physiological Assessment of Intermediate Coronary Lesions—A Non-Inferiority Meta-Analysis and Systematic Review

Background: Wire-based methods-fractional flow reserve (FFR) and instantaneous wave-free ratio (iFR) are the gold standard for physiological assessment of intermediate coronary lesions, but procedural complexity limits their use. Angiography-derived methods estimate FFR without a pressure wire or hyperemic agent. Direc...

Jayesh Mittal, Oscar R. Rivera, Isabela Carvalhal et al. · 0 citations

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