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Author

Irena Leite

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Open access Aug 2026

Adenosine 5′-Carboxamide-Based Inhibitors of METTL1

METTL1 is the human RNA methyltransferase that catalyzes the methylation of N7-guanosine in RNA. Overexpression of METTL1 has been linked to cancer, and increasing evidence supports the therapeutic potential of METTL1 inhibition in oncology. In this study, we have optimized a series of adenosine 5′-carboxamide derivati...

O. Bobiļeva, Francesco Nai, Sandija Niedrite et al. · 0 citations

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