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The investigated VDR variants do not appear to independently influence MS susceptibility, specific genotype combinations and alleles may contribute to the clinical expression of the disease, and the results support a potential role for vitamin D signalling in shaping MS heterogeneity.
Migraine is one of the main causes of neurological disability, especially in young adults. Recent developments in preventive migraine therapies have improved outcomes for many patients, while highlighting the need for additional therapeutic options for those who remain refractory to pharmacological prophylaxis. Repetit...
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