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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

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Inemai Ezhil

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Review Open access Sep 2026

CD200–CD200R as a myeloid immune checkpoint in solid tumors: mechanisms, context-dependent functions, and therapeutic opportunities

CD200 and its receptor CD200R form a myeloid-centered immune checkpoint that normally restrains myeloid activation and limits tissue damage, but many solid tumors co-opt this pathway to suppress antitumor immunity. CD200–CD200R signaling is highly context-dependent, varying even among models of the same cancer type. In...

M. Sahu, Inemai Ezhil, Venu Akkanapally et al. · 0 citations

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