Author

Iglika Sotkova-Ivanova

2 papers indexed here

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Review Open access Aug 2026

JAK2 V617F Clonal Dynamics from Clonal Hematopoiesis to Myeloproliferative Neoplasms: A Systems Biology Review of Digital PCR-Based Molecular Monitoring

Clonal hematopoiesis of indeterminate potential (CHIP) is an age-associated premalignant state defined by somatic mutations in hematopoietic cells at a variant allele frequency (VAF) ≥2% in the absence of overt hematologic malignancy. Among CHIP-associated mutations, JAK2 V617F is of particular interest because it occu...

Hristo Ivanov, Iglika Sotkova-Ivanova, V. Goranova-Marinova · Applied Sciences · 0 citations

Open access Sep 2026

Population-Specific Pharmacogenetic Variants Associated with Chemotherapy Response in the Bulgarian Population

Background/Objectives: Pharmacogenetic variability influences the efficacy and toxicity of anticancer therapies. However, Eastern European populations remain underrepresented in pharmacogenetic databases. This study aimed to characterize pharmacogenetic variants relevant to chemotherapy response in the Bulgarian popula...

Nelly N. Miteva-Marcheva, Hristo Ivanov, Iglika Sotkova-Ivanova et al. · Pharmaceuticals · 0 citations