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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

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Ibrahim Mustufa Topiwala

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Review Open access Sep 2026

Hypoxic cancer stem cell–immune niches in the tumor microenvironment: a Systematic Review of mechanisms and therapeutic implications

Background Hypoxia, cancer stem cell (CSC) plasticity, and immune suppression are established features of the tumor microenvironment, but their integration within the same biological systems has not been comprehensively synthesized. This systematic review evaluated whether hypoxia or hypoxia-associated signaling coordi...

Prasanna Appiya Premvignesh, Abubakker Siddiq Mohamed Hameed, Ibrahim Mustufa Topiwala et al. · 0 citations

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