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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Ian G. Ganley

h-index 4 View on Semantic Scholar

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Review Aug 2026

Regulation and roles of mammalian mitophagy.

Current understanding of PINK1-Parkin-dependent and independent mitophagy pathways are summarized, highlighting mechanistic distinctions and coordinated regulation, as well as the expanding therapeutic potential of targeting mitophagy in disease.

S. Martens, Ian G. Ganley · 0 citations
Open access Aug 2026

NLRX1 is an essential, druggable regulator of mitochondrial permeability transition

NLRX1 is established as an essential, CypD-independent regulator of mitochondrial permeability transition and provide brain-penetrant chemical tools to interrogate this biology.

Rachel E. Peltier-Heap, David W. Frederick, R. Pickering et al. · 0 citations

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