Author

Ian G. Barr

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Review Open access Sep 2026

Reassortment of Highly Pathogenic Avian Influenza as a Driver for Zoonotic Spillover, Asia

This article argues that reassortment, rather than point mutation alone, might be an underrecognized driver of zoonotic risk in endemic H5N1 lineages and is reshaping those lineages, and examines why such events might be underrecognized in settings with entrenched poultry influenza.

A. M. Byrne, Lorcan Carnegie, N. Lewis et al. · Emerging Infectious Diseases · 0 citations

Open access Jul 2026

Epistasis facilitates the long-term antigenic evolution of the influenza B virus hemagglutinin

This study identifies critical similarities and differences with A(H3N2) evolution and demonstrates the role of epistasis in balancing antigenic novelty with viral fitness, and supports the development of genotype-to-phenotype prediction tools, but such predictions need to capture the complex outcomes of epistasis.

Lara S. U. Schwab, Ruo-Peng Xie, Ellie Reilly et al. · bioRxiv · 0 citations