Open access
Jul 2026
Disrupting Treg lineage stability elicits RORgT-mediated plasticity and enhances anti-tumor immunity.
These findings highlight Hh/Gli2 signaling in Tregs as a mechanistic regulator of immunogenicity in the TME and a potential therapeutic target to prime tumors for enhanced responsiveness for adjuvant treatments.
Courtney A. Swain, D. Hinshaw, Ian D. Miranda et al.
· Cell Death and Disease · 0 citations