Open access
Sep 2026
Discovery of a new class based on 6-methoxypyrimidine as efficient low weight reversible inhibitors of SARS-CoV-2 main protease (Mpro) with antiviral activity.
A low molecular weight non-peptide, heterocyclic inhibitor, that inactivates Mpro, an important enzyme for the viral cycle and its inhibition affects replication and infection propagation in SARS-CoV-2.
I. S. Fortes, M. Lopes, T. H. M. Fernandes et al.
· Bioorganic chemistry (Print) · 0 citations