In vitro and in vivo functional roles of three region 1 promoters in Escherichia coli K1 capsule gene cluster
Abstract Capsular polysaccharides are key virulence determinants in extraintestinal pathogenic Escherichia coli, protecting bacteria from host immune defences while modulating interactions with host tissues. In group 2 capsule gene clusters, transcription of region 1 genes required for capsule export is controlled by a...