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I. Nasrallah

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Open access Sep 2026

SynthPET: A 3D generative AI approach for FDG‐PET image synthesis from T1‐weighted MRI and ASL CBF in Alzheimer's disease

Fluorodeoxyglucose (FDG) positron emission tomography (PET) is widely used for detecting metabolic changes associated with neurodegeneration in Alzheimer's disease (AD) and other dementias but is costly and involves ionizing radiation. Here we developed SynthPET, a multimodal deep learning framework that synthesizes FD...

Xavier Beltran-Urbano, Katie R. Jobson, I. Nasrallah et al. · 0 citations
Preprint Aug 2026

GenFAR: A generalized representation of brain structure, derived from 49,246 multi-cohort MRIs via deep learning

GenFAR, a modular deep learning framework that learns general, clinically informed features from brain MRIs, is introduced, showing that using the learned feature representation can substantially increase the sample efficiency of secondary deep learning training tasks and models, as well as improve their accuracy.

V. Bashyam, G. Erus, Jun-Hao Wen et al. · 0 citations
Open access Aug 2026

Opioid Use Disorder is Associated with Lower Resting-State Brain Network Segregation

Findings identify altered network segregation as a potential neurobiological marker of OUD and suggest that restoration of brain network specialization is a measurable target of OUD treatment and potentially recovery.

Delaney McKinstry, Xin-Yi Li, A. Ramos-Rolón et al. · 0 citations
Open access Jul 2026

Clinicopathologic Evaluation of Amyloid Clearance in Alzheimer Disease

In this case report, areas of extensive amyloid clearance following amyloid targeting therapy were associated with less downstream neuropathological change and appear to preferentially occur in gyral crests.

Christopher A. Brown, John L. Robinson, Sandhitsu R. Das et al. · 0 citations

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