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I. Maremmani

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Open access Oct 2026

Stress-Driven Brain Remodeling in Opioid Use Disorder: Toward a Neuroprogressive Model

Background: Opioid use disorder (OUD) is classically understood through reward dysregulation, opponent processes, and allostatic adaptation, but these models only partly account for the persistent cognitive, affective, and stress-regulatory abnormalities observed in some individuals with long-standing OUD. Methods: Thi...

F. Della Rocca, I. Maremmani, M. G. Carbone et al. · 0 citations
Open access Jan 2026

From Falls to Frontal Lobe Dysfunction: A Case Report on the Neurodevelopmental Impact of Pediatric Traumatic Brain Injury

The case focuses on a young adult male who sustained two head injuries in early childhood, with debilitating FLS symptoms, including marked emotional lability and executive function deficits, emerging at age 17, and a tailored pharmacological intervention strategy, focusing on mood stabilization and emotional regulatio...

M. G. Carbone, A. Bellini, Rossella Miccichè et al. · 0 citations

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