Open access
Apr 2025
Cytomegalovirus-induced T cell responses accelerate Alzheimer’s disease progression in mice
Using transgenic 3xTg-AD mice, systemic infection with the β-herpesvirus murine cytomegalovirus (MCMV) accelerates the development of cognitive decline, tauopathy, and synaptic loss in the hippocampus, all of which are key features of AD.
M. Marsden, J. E. McLaren, Ryan J. Bevan et al.
· bioRxiv · 3 citations