Sep 2026
Abstract B143: Functional screening of Arid1a-deficient pancreatic adenocarcinoma using the MAPS platform
Pancreatic ductal adenocarcinoma (PDAC) is an aggressive malignancy with limited therapeutic options. Approximately one-third of PDAC tumors harbor alterations in chromatin-remodeling genes, including loss-of-function mutations in ARID1A occurring in approximately 8% of cases. However, actionable vulnerabilities...
Wen-Jia Wang, Olivia Schmidt, S. Blick-Nitko et al.
· Cancer Research · 0 citations