Open access
Sep 2026
A novel framework leveraging non-causal associations reveals shared pathways linking inflammation and cancer risk
This work proposes a framework for identifying confounders of two non-causally related traits by employing cross-trait pleiotropy analysis to detect genetic loci that affect both traits and multi-trait colocalisation to identify molecular phenotypes mediating these effects.
J. Yarmolinsky, F. Cavallo, F. Koskeridis et al.
· medRxiv · 0 citations