Determination of a mutational status of the BRAF gene in patients with metastatic colorectal cancer in routine clinical practice: results of a survey of doctors in the Russian entities
Background: colorectal cancer (CRC) is one of the most common cancers in developed countries. The BRAF V600E mutation found in 8-10% of cases of metastatic CRC (mCRC) is a diagnostic, predictive and prognostic marker of the disease course. V600E (i. e., valine replacement with glutamic acid) is the most common CRC-asso...