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Author

Hyunjin Yeo

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Sep 2026

EGR1 coordinates a nuclear IL-33-phosphorylated STAT3 transcriptional complex to promote IL31 expression in TLR1/2-activated keratinocytes.

Interleukin (IL)-31 is a pruritogenic cytokine implicated in atopic dermatitis (AD), but its transcriptional regulation in epidermal keratinocytes remains unclear. We investigated whether early growth response 1 (EGR1) links Toll-like receptor (TLR)1/2 signaling to IL31 expression through nuclear IL-33 and signal trans...

Euitaek Jung, Ye-Na Choi, Junekyu Han et al. · 0 citations

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