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Author

Hyungmin Jeong

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Open access Oct 2026

βKlotho filters ligand-independent FGFR1/4-PLCγ signaling to prevent aberrant constitutive Ca2+ entry.

Fibroblast growth factor receptors 1 and 4 (FGFR1/4) regulate diverse cellular processes, including proliferation, differentiation, and metabolic homeostasis. Although ligand-dependent FGFR signaling has been extensively characterized, the signaling properties of these receptors in their ligand-independent state remain...

Bao T. N. Dang, Phan Anh Nguyen, Su-Bo Lee et al. · 0 citations

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