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Hutheyfa A. Al Salih

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Open access Jul 2026

Modulatory Effects of IL-24 on Autophagy and Apoptosis in Large Cell Lung Carcinoma

It is validated that IL-24 exerts potent anti-cancer activity in primary LCLC by triggering excessive, toxic autophagy that drives past a cytoprotective survival threshold, successfully engaging the ATG4/ATG5 molecular switch to orchestrate a fatal transition into the intrinsic mitochondrial apoptotic pathway.

Hutheyfa A. Al Salih · 0 citations

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