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Author

Huidi Jiang

2 papers indexed here

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Sep 2026

Endogenous metabolite bilirubin suppresses esophageal squamous cell carcinoma by activating PERK-dependent translational repression.

It is found that higher serum bilirubin levels were associated with improved overall survival and served as an independent favorable prognostic factor in ESCC and bilirubin suppresses tumor progression via PERK-mediated translational repression, providing mechanistic insights into the role of the PERK-eIF2α axis in bil...

Min-Lei Dong, Ping Li, Jun Luo et al. · 0 citations
Jul 2026

Mitochondrial fission-mediated podocyte dysfunction via CaMKII/Drp1 signaling pathways contributes to lenvatinib-induced renal injury.

Findings provide the first evidence suggesting that increased mitochondrial fission via CaMKII/Drp1 signaling pathways in podocytes contributes to lenvatinib-induced kidney injury, and identify metformin as a clinically viable treatment option for lenvatinib-induced renal injury.

Shuanghui Lu, Yue-Ping Qiu, Yujia Chen et al. · 1 citation

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