Author

Hui Wang

2 papers indexed here

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Open access Aug 2026

Lead optimization of 3-indoleacetonitrile identifies candidate compounds with improved anti-influenza activity and safety profiles

Introduction Influenza A virus (IAV) remains a major respiratory pathogen that causes substantial morbidity, mortality, and socioeconomic burden worldwide. Although several antiviral agents are available for clinical use, their effectiveness is often compromised by the emergence of drug-resistant variants, limited ther...

Xian-Feng Hui, Shi-Huan Ding, Bing-Qi Yan et al. · Frontiers in Microbiology · 0 citations

Open access Aug 2026

The APC/C subunit APC7 exerts antiviral effects by targeting the adaptor protein MAVS

It is demonstrated that APC7 potentiates the antiviral response through activation of MAVS-mediated signaling, which provides new insights into the regulatory mechanisms of innate immunity and viral infections.

Rui Su, Aiping Sun, Yifan Niu et al. · Frontiers in Immunology · 0 citations