Author

Huiling Shu

2 papers indexed here

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Sep 2026

Multilevel ensemble for genome-wide prediction of cell-specific G-quadruplexes utilizing transformed sequences and enhanced chromatin accessibility with G4Beacon2.

G-quadruplexes (G4) are prevalent non-B DNA structures playing crucial biological roles in cells. Although experimental technologies for G4 identification in vitro and in vivo are advancing, computational prediction methods are increasingly preferred for their efficiency, convenience, and cost effectiveness. However, e...

Tian-Tong Tao, Rong Zhang, Hui-Ling Shu et al. · Genome Research · 0 citations

Open access Aug 2026

MTCH2 acts as a novel inhibitory receptor to suppress germ cell mitophagy by tethering BECN1, thereby maintaining mitochondrial homeostasis and male fertility

These findings establish MTCH2 as an essential negative regulator of mitophagy that partners with BECN1 to maintain mitochondrial homeostasis, thereby ensuring normal spermatogenesis and male fertility.

Mengxing Cai, Rui-Fang Ren, Huiling Shu et al. · Cell Death & Disease · 0 citations