Oleanolic Acid Alleviates Diabetic Nephropathy by Inhibiting Ferroptosis Involving the Activation of the NRF2/HO-1 Pathway
Oleanolic acid (OA), a pentacyclic triterpenoid found in agricultural products such as grapes and olives, exhibits potential in alleviating diabetic nephropathy (DN). We validated its renoprotective effects using high-fat diet/streptozotocin (HFD/STZ)-induced diabetic mice and high glucose-stimulated HK-2 cells. Netw...