Review
Open access
Sep 2026
Precision Nanodelivery Enables Spatiotemporal Control of NAD⁺ Metabolism in Ageing and Disease
Abstract Declining nicotinamide adenine dinucleotide (NAD⁺) represents a conserved metabolic hallmark of ageing, organ dysfunction and numerous acute and chronic disorders. NAD⁺ metabolism exhibits pronounced spatial, cell-type and subcellular compartmentalization in pathological tissues, orchestrating DNA repair, redo...
Ze-Rong Pei, Xue-Mei Wang, Feng-Ni Liang et al.
· International Journal of Nan... · 0 citations