Hui-Lai Lv

Prognostic Stratification of Adjuvant Immunotherapy After Neoadjuvant Chemoimmunotherapy and Quality Surgery in LA-ESCC.

BACKGROUND In locally advanced esophageal squamous cell carcinoma (LA-ESCC), neoadjuvant chemoimmunotherapy (NCIT) plus high-quality surgery (R0 resection with systematic lymphadenectomy >19 nodes) is a promising strategy. However, the value of adjuvant immunotherapy remains unclear. This study aimed to evaluate the as...

Early recurrence patterns after neoadjuvant chemoradiotherapy and chemoimmunotherapy in esophageal squamous cell carcinoma: A multicenter study.

OBJECTIVE To compare early recurrence patterns and survival outcomes between neoadjuvant chemoimmunotherapy (NCIT) and neoadjuvant chemoradiotherapy (NCRT) in patients with locally advanced esophageal squamous cell carcinoma (ESCC). METHODS This retrospective cohort study included 1428 patients with stage IIB-IVA ESC...

LAMB1 accelerates esophageal squamous cell carcinoma by triggering JAK2/STAT3 signaling

Trends and Projections of Esophageal Cancer Incidence and Mortality in China, 1990 to 2050: An Analysis of the Global Burden of Disease Study 2023.

GOALS The study aims to analyze and project esophageal cancer trends in China from 1990 to 2023 using GBD 2023 data. BACKGROUND Esophageal cancer (EC) remains a major public health challenge in China. Updated evidence on long-term trends and future burden is needed to inform prevention and control strategies. METHO...