Hui-Hui Wu

Discovery of A Safe and Effective Hemipteran Insecticide: α6 nAChR-Targeting Non-Mesoionic Scaffold

Triflumezopyrim, a mesoionic insecticide targeting nAChRs, effectively controls resistant hemipteran pests like planthoppers but raises concerns over non-target toxicity, especially to honeybees. In this study, we identified compound Q1, a pyrido[2,3-d]pyrimidine-2,4-dione derivative, which exhibits slightly superior...