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Author

Hui-Hong Wang

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2 papers indexed here

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Aug 2026

Burden of Stroke and Its Subtypes in Young Adults in China: A Systematic Analysis from 1990 to 2023 and Projections to 2050.

Global and Chinese overall stroke age-standardized incidence rates declined, but new cases increased globally, and ischemic stroke age-standardized incidence rose significantly in China, and China's proportion of global cases and deaths decreased.

Fei-Hong Hu, Hai-Lin Lu, Hong Xu et al. · 0 citations
Aug 2026

Discovery of a novel 10-hydroxy-12-methyl-substituted evodiamine derivative with anti-hepatocellular carcinoma activity through multi-pathway modulation involving suppression of PKA/AKT signaling cascades and moderate Topo I inhibition.

Z4 more effectively inhibited proliferation and migration/invasion of BEL-7404 and HuH-7 cells than sorafenib, while inducing cell cycle arrest, mitochondrial dysfunction, reactive oxygen species (ROS) accumulation, and apoptosis, and provides a promising lead compound Z4 for anti-HCC drug discovery.

Yan Peng, Zi-Xuan Li, Hanxuan Mo et al. · 0 citations

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