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Author

Huifen Ma

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Oct 2026

Sesquiterpenes from the rhizomes of Acorus calamus var. angustatus Besser and their neuroprotective properties.

Five sesquiterpenes were isolated from the dried rhizomes of Acorus calamus var. angustatus Besser. Their structures were determined by spectroscopic analysis and ECD calculations, including one new eudesmane-type sesquiterpene, 2-hydroxy-eudesmane K (1), and four known compounds: eudesmane K (2), isocalamendiol (3), a...

Yuan-Fang Zhang, Yi-Nan Zhao, Yao Ren et al. · 0 citations
Aug 2026

Deep learning-driven discovery and optimization of natural LSD1 inhibitors for the treatment of Alzheimer's disease.

This study provides a generalized DTA tool for early-stage drug development, and identifies S3 as a novel LSD1 inhibitor with potent anti-AD efficacy, by addressing unmet demands for AI-assisted anti-AD lead discovery.

Zhong-Hua Li, Tiancheng Sun, M. Han et al. · 0 citations

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