Amphiphilic Pillar[5]arene-Based Pt(II)-Coordinated Dual-Cavity Metallacycle: Construction and Application in Enhanced Mitochondrial Photodynamic Cancer Therapy.
Photodynamic therapy (PDT) has some major problems that seriously limit its use in treating tumors. For example, the photosensitizers tend to clump together, which causes fluorescence to drop sharply. They also do not produce enough singlet oxygen, and they cannot accurately reach the specific parts of cancer cells tha...