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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Hugo Kocek

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Open access Aug 2026

First-in-class inhibitors of the protein lysine methyltransferase METTL21A.

A crystal structure of METTL21A is solved in complex with 6m, providing structural insight into ligand recognition and supporting further structure-guided optimization and establishing a biochemically and structurally validated starting point for probing METTL21A function and a foundation for the development of cellula...

Hugo Kocek, Michal Vaško, M. Dejmek et al. · 0 citations

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