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Author

Huawei Zhang

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Aug 2026

Discovery of a new P450 enzyme DkpdB for cyclo(Trp-Phe) dimerization in the marine strain Aspergillus sydowii MNP-2.

A novel cytochrome P450 monooxygenase DkpdB was originally discovered in the marine-derived fungus Aspergillus sydowii MNP-2 and shown to catalyze the formation of the DKP dimer WIN 64821 from cyclo(Trp-Phe) through a proposed C3-C3' oxidative coupling reaction.

Huawei Zhang, Xiao-Ying Wang, Yao Ding · 0 citations
Review Aug 2026

Aspergillus-derived indole diketopiperazines (IDKPs): chemical diversity, biosynthetic logics, and therapeutic potential.

This review emphasizes the unique capacity of Aspergillus species to generate structurally diverse IDKPs and highlights the potential of genome mining and biosynthetic gene cluster (BGC) analysis for uncovering previously unexplored IDKP biosynthetic pathways.

Jingxin Tian, Huanhuan Yang, Huawei Zhang · 0 citations
Aug 2026

A Novel, Simple, and Highly Efficient Dual-sgRNA CRISPR/Cas9-Based Editing System in the Filamentous Fungus Fusarium oxysporum

A novel highly efficient CRISPR/Cas9-based dual-sgRNA expression editing system for F. oxysporum suitable not only for single-gene editing but also for large-fragment deletion and multiplex gene editing, although the editing efficiency is somewhat lower.

Wangjie Zhu, Jiao Liao, Yuanyuan Liu et al. · 0 citations

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