Aug 2026
An inherent T cell-activating mRNA delivery carrier for in vivo CAR T generation.
Qiannan Cao, Yingli Yao, Wenming Zheng et al.
· Nature Materials · 0 citations
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Review
Jul 2026
Polymeric Delivery Vehicles for Nucleic Acid Vaccines: Design Strategies and Biological Barriers.
This review systematically dissects how functional polymer engineering-including interfacial shielding, targeted ligand modification, membrane perturbation, and stimuli-responsive disassembly-facilitates systemic circulation, antigen-presenting cell uptake, endosomal escape, and intracellular cargo release.
Pijun Su, Hui-Lin Yuan, Kang-Xin Zhang et al.
· ACS Applied Materials and In... · 0 citations
Review
Jul 2026
Non-viral and non-lipid nanoparticles for RNA therapeutics: Design, applications, and preclinical studies.
This review examines non-viral and non-lipid RNA nanocarriers from mechanistic and translational perspectives and highlights non-viral and non-lipid nanocarriers as complementary platforms for context-specific RNA therapy.
Mingxia Jiang, Qiannan Cao, Huapan Fang et al.
· Journal of Controlled Releas... · 0 citations