Atherosclerotic cardiovascular disease (ASCVD) is a leading cause of global mortality. Despite advances in primary prevention and acute management, patients with established ASCVD face high residual risks for recurrent major adverse cardiovascular events (MACEs) and chronic kidney disease (CKD) progression. Life’...
Z. Yuan, X. Lu, G. Yuan et al.· European Heart Journal· 0 citations
Lipoprotein(a) [Lp(a)] is a well-recognized hazard indicator for cardiovascular disease (CVD) and all-cause mortality. Higher Lp(a) levels are robustly correlated with adverse cardiovascular outcomes. However, Lp(a) exhibits notable ethnic heterogeneities, with most epidemiological studies conducted primarily in...
G. Yuan, X. Lu, Z. Yuan et al.· European Heart Journal· 0 citations
Findings indicate that long-term PM2.5 exposure is associated with prevalent MetS and subsequent CVD risk among individuals with MetS, particularly among genetically susceptible individuals, with DNA methylation potentially serving as an epigenetic link in these associations.
Zi-Yue Li, Hao-Zhang Huang, Jin-Ming Chen et al.· Ecotoxicology and Environmen...· 0 citations
Higher LE8 scores were associated with lower risks of MACE and CKD in ASCVD patients, and high LE8 achievement may attenuate risks toward non-ASCVD levels.
This study reveals that SRA1 is a novel therapeutic target for PPD, which enhances the understanding of its molecular aetiology and the development of therapeutic strategies.
Ming Chen, Qinlin Wei, Hao-Wen Li et al.· npj Mental Health Research· 0 citations
Findings highlight significant sex differences in the effect of depression on CHD risk, which could inform sex-specific preventive strategies for reducing the cardiovascular burden in individuals with depression.
Haozhang Huang, Ming Chen, Xiao-Zhao Lu et al.· European Journal of Preventi...· 0 citations
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