Review
Open access
Sep 2026
Peroxisomes in Alzheimer’s disease: emerging mechanistic insights and therapeutic opportunities
Alzheimer’s disease (AD) is characterized by amyloid-β (Aβ) deposition, tau pathology, synaptic injury, neuroinflammation, oxidative stress, and disrupted organellar homeostasis. Peroxisomes maintain lipid and redox balance through very-long-chain fatty acid (VLCFA) β-oxidation, plasmalogen biosynthesis, and reactive o...
T. Liu, Yi-Ran Liu, Yi-Chi Zhang et al.
· Frontiers in Aging Neuroscie... · 0 citations