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Huai-Jue Qiu

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Review Open access Sep 2026

T-cell senescence and immunosenescence in chronic oral mucosal inflammatory diseases: mechanisms and therapeutic implications

Abstract Background The oral mucosa is a dynamic barrier. T‑cell dysregulation contributes to chronic oral mucosal inflammatory diseases, but the role of age‑related immune remodeling remains unclear.. Method We performed a narrative review of PubMed/Medline (1972–2026) on T‑cell subsets, immunosenescence, exhaustion,...

Huai-Jue Qiu, Yi-Lin Luo, L. Pu et al. · 0 citations
Review Open access Aug 2026

Gut microbiota–mitochondria–barrier–multiorgan axis: a network-based hypothesis for systemic injury

It is discussed how circulating metabolites and mtDNA could serve as candidate monitoring biomarkers to turn this conceptual network into a testable, quantitative model and a multi-dimensional research framework while stressing that any clinical application must await prospective validation.

Ya-Chao Li, Huai-Jue Qiu, Xiang Gao et al. · 0 citations

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