Pathological cardiac fibrosis and hypertrophy, key contributors to adverse remodeling that drives heart failure (HF), are not adequately targeted by current therapies. We identified tRNA-Asp-GTC-3′tDR, an ischemia-induced tRNA-derived small RNA (tDR), as an endogenous regulator of both remodeling processes across cardi...
Tian Hao, Jin Li, Kaushik V. Amancherla et al.· bioRxiv· 0 citations
This review comprehensively explores the roles of noncoding RNAs (ncRNAs) in cardiovascular diseases (CVDs), highlighting their involvement in major pathological programs and cellular functions. The diverse types of ncRNAs, including microRNAs (miRNAs), long noncoding RNAs (lncRNAs), and circular RNAs (circRNAs), and t...
Bing-Chuan Geng, Peng Chen, De-Qiang Li et al.· The Journal of Cardiovascula...· 0 citations
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