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Author

Hua-Liang Lin

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Open access Oct 2026

Prioritizing and integrating age- and sex-specific modifiable risk factors related with depression: a prospective cohort study of 428,078 adults

Abstract Aims To systematically identify and prioritize age- and sex-specific modifiable risk factors for incident depression, and to characterize integrated risk patterns to pinpoint high-risk populations across different life stages. Method Using data from 428,078 participants in a cohort, incident depression was ide...

Lan Chen, Sheng-Tao Wei, Jin-De Zhao et al. · 0 citations
Aug 2026

Integrated Plasma Proteomics and Metabolomes Reveal Potential Biomolecules Linking PM2.5 to Depression.

The biomolecular pathways linking fine particulate matter (PM2.5) and its constituents to depression remain elusive. With 24,940 depression-free participants in the UK Biobank, exposure to PM2.5 and its 5 constituents (ammonium, nitrate, sulfate, elemental carbon, and organic carbon) was estimated. We integrated Olink-...

Lan Chen, Dashan Zheng, Sheng-Tao Wei et al. · 0 citations
Aug 2026

Healthy lifestyle and related metabolomic signatures associated with decreased risk and delayed progression of type 2 diabetes mellitus transitions: a large prospective cohort study.

The findings highlight the significance of adherence to a healthy lifestyle in preventing the onset and progression of T2DM from behaviors and metabolomics perspectives.

Peng Hu, Yuqin Wang, Guzhengyue Zheng et al. · 0 citations

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