PPARγ signaling pathway: strategies and limitations of natural compounds in the treatment of ulcerative colitis
Ulcerative colitis (UC) is a chronic, relapsing inflammatory bowel disease characterized by persistent inflammatory activation, immune dysregulation, gut microbiota dysbiosis, and damage to the mucosal barrier. Peroxisome proliferator-activated receptor gamma (PPARγ) is a key nuclear receptor involved in maintaining...