Author

Hua-Cheng Luo

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Open access Aug 2026

Site-specific N6-methyladenosine fine tunes CTCF/cohesin-defined enhancer-promoter interactions and oncogenic transcription program

Abstract N6-methyladenosine (m6A) of RNAs plays an important role in RNA stability and gene expression. However, it remains unknown how site-specific m6A on individual RNA is decoded to regulate chromatin architecture and transcriptional reprogramming. Here, we show that m6A modification of HOTTIP lncRNA is highly enri...

Su-Ming Huang, Hua-Cheng Luo, Karina Hamamoto et al. · Research Square · 0 citations

Open access Jul 2026

Protocol for high-resolution mapping of RNA-associated chromatin using chromatin isolation by RNA purification-tag

A protocol for integrating RNA hybridization with in situ tagmentation using chromatin isolation by RNA purification-tag (ChIRP-Tag) is presented, which captures RNA-associated chromatin with high sensitivity and spatial resolution across various cell types.

Ruishuang Fu, Rongjie Zhao, Huimin Yang et al. · STAR Protocols · 0 citations