Author

Hua Chang

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Meta-analysis Open access Aug 2026

Study-Aware Meta-Analysis Reveals a Recurrent Proteostasis Program and Context-Dependent Gene-Level Responses in Bovine Heat-Stress Transcriptomes

Background/Objectives: Bovine heat-stress RNA-seq studies differ in tissue, age, physiological state, and exposure design. We asked which responses recur across these contexts and which depend on the evidence base. Methods: We reprocessed 107 libraries from five in vivo Bos taurus studies and synthesized within-study h...

Xiaotong Zhao, Hua Chang, Quan-Peng Zhang et al. · Genes · 0 citations

Review Open access Jul 2026

Emerging Environmental Toxicants Undermine Reproductive Success in Aquatic Animals: A Narrative Review

Aquatic animals are increasingly exposed to complex mixtures of emerging environmental toxicants, including microplastics, nanoplastics, per- and polyfluoroalkyl substances (PFAS), and endocrine-disrupting chemicals (EDCs). This raises serious concerns for reproductive health, offspring survival rates, and long-term po...

Yu-Chen Du, Hua Chang, Qiu-Yue Wang et al. · Journal of Xenobiotics · 0 citations