Open access
Aug 2026
Tcf15 promotes an open nucleolar chromatin state to safeguard ribosome biogenesis and genome stability in mouse embryonic stem cells
These findings add a new regulatory layer of chromatin state in rDNA of stem cells, and reveal a previously unrecognized phenotypic consequence of defective RiBi in ESCs.
Yuping Dong, Yi-Min Chen, Min Tang et al.
· PLoS Biology · 0 citations