Hu-Chen Hu

Metabolic reprogramming, ferroptosis, and tumor-associated macrophage states: mechanistic crosstalk and therapeutic prospects

Tumor metabolic reprogramming serves as a fundamental driver of malignancy, fueling cancer cell growth while reshaping the immune landscape through metabolite accumulation. Ferroptosis, an iron-dependent form of regulated cell death, is intricately linked to these metabolic shifts. In the tumor microenvironment, tumor-...