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Sponsored AI Networking Cookbook: Practical recipes for AI-assisted network automation and development AI Networking Cookbook: Practical recipes for AI-assisted network automation and development

Author

Hu Chen

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Open access Oct 2026

Decline of chaperone-mediated autophagy in aging impairs macrophage clearance of senescent cells.

Autophagy dysfunction and senescence are established drivers of aging, but their potential interaction remains poorly understood. Here we show that age-related decline of chaperone-mediated autophagy (CMA), a pathway for selective lysosomal protein degradation, changes senescent cell properties and impairs their immune...

Rebecca Sereda, Kristen Lindenau, Antonio Díaz et al. · 1 citation
Open access Aug 2026

Deep-learning-enabled multi-omics analyses for prediction of future metastasis in cancer

EmitGCL is developed, a deep-learning framework to predict metastasis and related biomarkers using cancer single-cell sequencing data, enabling and validating the discovery of occult metastases and breast cancer metastasis biomarkers.

Xiaoying Wang, Maoteng Duan, Anthony J. Snyder et al. · 0 citations
May 2025

Deep-learning-enabled multi-omics analyses for prediction of future metastasis in cancer

EmitGCL, a deep-learning framework that accurately predicts future metastasis and its corresponding biomarkers, is presented and YY1 transcription factor is demonstrated as a key driver of breast cancer metastasis which was validated through in-silico and CRISPR-based migration assays, suggesting that YY1 is a potentia...

Xiaoying Wang, Maoteng Duan, Po-Lan Su et al. · 0 citations

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