Hou-Shan Fang

Senescent immune cells, inflammaging, and bone loss: therapeutic potential and translational challenges of senolytics in osteoporosis

A structured research roadmap is proposed—centered on fate-mapping, lineage-specific depletion, and single-cell multi-omics—to convert the prevailing hypothesis into experimentally testable and clinically actionable evidence, while delineating the translational challenges that must be overcome to achieve precision seno...