Author

Hongyan Sun

2 papers indexed here

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Open access Sep 2026

An endoplasmic reticulum-enriched nanogel couples ferroptotic tumor damage with macrophage reprogramming for triple-negative breast cancer immunotherapy

Triple-negative breast cancer (TNBC) is characterized by severely immunosuppressive tumor microenvironment (TME), which leads to tumor ferroptosis resistance and dominant protumor M2 macrophages, restraining innate-to-adaptive antitumor immune cascade. Herein, an endoplasmic reticulum (ER)-enriched pH/redox-sensitive S...

Heying Chen, Yi-Lu Ni, Jia-Ruo Tang et al. · Bioactive Materials · 0 citations

Open access Aug 2026

Chemi-Proteome Language Attention Network Empowers Fragment-Based Ligand Interactome and Binding Sites Discovery with Evidence

By learning directly from cellular chemoproteomics, C-PLANK moves beyond isolated interaction prediction toward cellular interaction-state modelling, establishing a computational foundation for future digital-twin frameworks in drug discovery.

Bing-Song Liao, Ji-Xiao He, Mingzhu Zhao et al. · bioRxiv · 0 citations