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Hongxin Xiang

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Book Open access Aug 2026

DiffPro: Decoupled Generative Prior with Diffusion Models for Efficient Few-Shot Drug Synergy Prediction

DiffPro, a novel framework that integrates a Latent Diffusion Model (LDM) as a structural prior, confirms that the diffusion prior successfully regularizes the latent space, mitigating task representation collapse and enabling robust, high-precision predictions for combination therapy design.

Shu-Ting Jin, Xu Guo, An-Qi Huang et al. · 0 citations
Jul 2026

A Multi-Modal Cyclic Peptide Representation Learning Framework for Membrane Permeability Prediction.

MultiMol is a multimodal framework that integrates SMILES sequences, molecular images, molecular graphs, and 3D conformations through tailored pre-training tasks and a scalable fusion mechanism, and consistently outperforms existing methods in cyclic peptide permeability prediction.

Haowen Chen, Xiuxiu Chao, Weihao Ou et al. · 0 citations

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