Honglin Song

Responsive reconstruction-driven autocatalysis DNA circuit for efficient and amplifiable electrochemical biosensing.

To overcome low strand utilization and slow kinetics in traditional entropy-driven DNA circuits, herein we propose a novel responsive reconstruction-driven Autocatalysis DNA Circuit (rrADC) for constructing highly sensitive electrochemical biosensor. Using 17β-estradiol as a targeted ligand, the specific ligand-aptamer...