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Author

Hongchen Zhang

2 papers indexed here

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Open access Sep 2026

Disrupting the BEX4-Mediated DNA Repair Rheostat with a Novel Inhibitor Suppresses Stemness and Enhances Chemosensitivity in Hepatoblastoma.

Cisplatin resistance in hepatoblastoma (HB) is a major therapeutic barrier. Emerging evidence suggests that cancer cells can activate DNA double-strand break repair pathways to evade chemotherapy-induced apoptosis and sustain stemness; however, the mechanisms underlying cisplatin resistance in HB remain poorly understo...

Ze-Yu Yan, Qian Wang, Jing Li et al. · 0 citations
Open access Aug 2026

Engineered Xenogeneic Bone Scaffold with IL‐10 Nanodelivery System: Immunomodulation and BMSC Fate Programming for Skull Defect Repair

ABSTRACT Skull defect reconstruction remains clinically challenging because current artificial implants lack bioactivity and produce radiological artifacts, whereas autologous bone grafts suffer from unpredictable resorption and infection. Here, we developed a multifunctional composite integrating antigen‐extracted xen...

Wei-Hao Lv, Lei Zhang, F. Fei et al. · 0 citations

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