Author

Hong-Yu Chen

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Open access Sep 2026

Highly efficient intranasal H5N1 vaccine based on a safe vesicular stomatitis virus (VSV) vector

The successfully developed novel 6-9ΔGΔ51+S226R-H5N1 vaccine candidate not only exhibits excellent safety and immunogenicity but also represents a powerful potential tool for the effective prevention and control of highly pathogenic avian influenza.

Ziteng Liang, Meng-Yi Zhang, Jie Zhang et al. · Signal Transduction and Targ... · 0 citations

Open access Sep 2026

A dimeric mRNA vaccine based on key-mutant and KP.3 RBDs induces broad-spectrum immunity and protects mice against JN.1 and XDV challenges

The design and preclinical evaluation of SV suggest that heterodimeric RBD architectures incorporating antigenically divergent variants may represent a generalizable platform for countering viral immune evasion, with implications for future SARS-CoV-2 variants and other rapidly evolving viral pathogens.

Jia-Li Xu, Rui Peng, Long-Hai Yuan et al. · Molecular Biomedicine · 0 citations